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Appetite Is Controlled by the Brain, Not Willpower Hunger and fullness are regulated by complex signals between the gut, pancreas, and brain—especially areas that control appetite, reward, and impulse regulation
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GLP-1 and GLP-1(9–36) are also cleaved by neutral endopeptidase (NEP24.11), yielding GLP-1(28–36), a 9–amino acid carboxy-terminal peptide with biological activity (11)